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- Andre Agassi Native tennis player philanthropist
- Greg Anthony Native basketball player
- Anna Ayala Native felon charged for larceny against Wendy's
- Big B Non-Native recording artist Suburban Noize Records
- Bobby Baldwin Non-Native poker player and casino executive
- Toni Basil Non-Native choreographer, musician
- David Beltran Non-Native business professional
- Benny Binion Non-Native owner of the Horseshoe casino
- Joey Bishop Non-Native entertainer The Rat Pack
- Sam Boyd Non-Native casino owner
- Toni Braxton Non-Native recording artist
- David Brenner Non-Native comedian
- Kurt Busch Native race car driver, NASCAR
- Kyle Busch Native race car driver, NASCAR
- Charlie Callis Native comic
- Charisma Carpenter Native actress
- Daveigh Chase Native actress
- Spencer Clark Native race car driver, NASCAR
- Norm Clarke Non-Native gossip columnist for the Las Vegas Review-Journal
- Rico Constantino Native wrestler
- Randall Cunningham Non-Native football player
- Tony Curtis Non-Native actor
- Jay Cutler Non-Native IFBB Professional Bodybuilder Mr. Olympia
- Laura Dahl Native fashion designer
- Moe Dalitz Non-Native developer casino owner/executive (Desert Inn)
- Baron Davis Non-Native basketball player
- Ricky Davis Native basketball player
- Sammy Davis, Jr. Non-Native singer and entertainer The Rat Pack
- Becky Delos Santos Non-Native model, Playboy Playmate
- Céline Dion Non-Native singer
- Leah Dizon Native model, singer
- Brandon Flowers Native musician The Killers
- Siegfried Fischbacher Non-Native entertainer Siegfried & Roy
- Tony Fredianelli Non-Native Musician Third Eye Blind guitarist
- John C. Fremont Non-Native explorer
- Danny Gans Non-Native Impersonator
- Brendan Gaughan Non-Native race car driver, NASCAR
- Jason Giambi Non-Native baseball player
- Oscar Goodman Non-Native attorney defense attorney for mafia figures, Mayor of Las Vegas
- Mikalah Gordon Native American Idol contestant
- Hank Greenspun Non-Native Newspaper publisher newspaper publisher and land developer
- Matthew Gray Gubler Native Actor
- Lonnie Hammargren Non-Native doctor, politician
- Carey Hart Native Pro Bmx Dirt Rider, motorcycle stunt rider
- Clint Holmes Non-Native singer, songwriter
- Roy Uwe Ludwig Horn Non-Native entertainer Siegfried & Roy
- Howard Hughes Non-Native billionaire casino owner and land developer
- Carl Icahn Non-Native Tycoon owner of Stratosphere and Arizona Charlies
- Jenna Jameson Native porn star
- Corinna Harney Jones Non-Native actress Playboy playmate
- Reggie Jackson Non-Native actor baseball player
- Morris R. Jeppson Non-Native Second Lieutenant Enola Gay bombing of Hiroshima
- Brian Kelly Non-Native football player
- Kirk Kerkorian Non-Native developer International Hotel
MGM Grand
- Gladys Knight Non-Native singer, actress
- Jimmy Kimmel Non-Native comedian Jimmy Kimmel Live
- B.B. King Non-Native Blues legend
- Jack Kramer Native tennis player
- Meyer Lansky Non-Native mobster financier
- T.J. Lavin Native
- Peter Lawford Non-Native actor The Rat Pack
- Robin Leach Non-Native writer TV show host
- Jerry Lewis Non-Native entertainer
- Liberace Non-Native entertainer
- Jon Lindquist Non-Native radio announcer
- King Lizzard Non-Native entertainer
- Larry Johnson Non-Native basketball player, NBA
- Stephanie Louden Native golfer, LPGA
- Greg Maddux Native pitcher, Major League Baseball
- Shawn Marion Non-Native forward, National Basketball Association played for UNLV
- Dean Martin Non-Native singer and entertainer The Rat Pack
- Angela Melini Non-Native actress, model, Playboy Playmate, entrepreneur
- Frank Mir Native Mixed Martial Artist former heavyweight champion in the UFC
- Kevin Mitnick Non-Native computer consultant hacker
- Pat Morita Non-Native actor
- Vince Neil Non-Native singer Mötley Crüe
- Wayne Newton Non-Native singer
- Paige O'Hara Non-Native actress
- Elvis Presley Non-Native singer
- Debbie Reynolds Non-Native entertainer
- Sig Rogich Non-Native political consultant founder of R&R Advertising
- Stephanie Romanov Native actress
- Kevin Rose Native actor founder of digg.com & Rev 3
- Frank Rosenthal Non-Native sports handicapper, casino manager
- Jay Sarno Non-Native developer Caesars Palace and Circus Circus
- Adam Seward Native football player
- Steve Schirripa Non-Native actor entertainment director and consultant for The Riviera
- Bugsy Siegel Non-Native mobster developer of the Flamingo
- Frank Sinatra Non-Native singer The Rat Pack
- Kevin Sorbo Non-Native actor
- Anthony Spilotro Non-Native Mafia enforcer
- Shannon Stewart Non-Native model, Playboy Playmate
- Mark Stoermer Native musician The Killers
- Bob Stupak Non-Native Casino developer Stratosphere, Vegas World
- Jerry Tarkanian Non-Native Basketball coach former UNLV Men's Basketball Head Coach
- Brian Thornton Non-Native developer of DoubleClick technology company, technology advocate
- Josh Towbin aka Chop Non-Native GM of Towbin Dodge, Rapper and Star of A&E's King of Cars
- Mike Tyson Non-Native boxer
- Robert Urich Non-Native actor television actor (Vega$)
- Ronnie Vannucci Native musician The Killers
- Del Webb Non-Native developer
- James Ronald Whitney Native film and television director
- Don White Non-Native real estate developer
- Brent Wilson Native musician Panic! at the Disco(former member)
- Steve Wynn Non-Native developer The Mirage, Treasure Island, Bellagio and Wynn Las Vegas
- Barry Zito Native baseball player
- Amber Tomcavage Native Cocktail Waitress Castmember of Big Brother 8
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