Academia

• Roland Frye, scholar
• Carol Garrison, president of UAB
• Kay Tipton, notable high school mathematics teacher

Arts & Literature

• John Beecher, activist poet
• Allen Barra, journalist, sports writer
• Steven Ford Brown, publisher, translator, writer
• Mark Childress, author
• Jon Coffelt, artist
• Clayton Colvin, artist
• Dennis Covington, journalist, writer
• Fannie Flagg, author, actress
• Frank Fleming, sculptor
• Charles Gaines, novelist, screenwriter
• Gail Godwin, novelist
• Spider Martin, photojournalist
• Robert R. McCammon, novelist
• Sena Jeter Naslund, author
• Walker Percy, author
• Howell Raines, former New York Times editor
• James Redfield, novelist
• Sonia Sanchez, poet
• Virginia Scruggs, photography
• Melissa Springer, photographer
• Margaret Walker, poet and author
• Tobias Wolff, author
• Daniel Wallace, novelist

Business & Economics

• A.G. Gaston, African-American businessman
• John M. Harbert, founder of Harbert International
• Elmer Harris, CEO of Alabama Power
• Wallace Malone, former CEO of SouthTrust Bank
• Brad Martin, CEO of Saks Incorporated
• Michael K. Powell, former FCC chairman
• Rufus N. Rhodes, founder of the Birmingham News.
• Richard M. Scrushy, founder of Healthsouth
• Donald Watkins, banker, attorney

Entertainment

• R.G. Armstrong, actor
• Steve Ashlee, director
• Amber Benson, actress
• Attitude, rapper
• Rick and Bubba, radio/tv personalities
• Bo Bice, singer, "American Idol" runner-up (Helena)
• Birmingham J, rapper
• Nell Carter, singer & actress
• Dorothy Love Coates, gospel singer
• Courteney Cox, actress
• Diana Degarmo, singer, "American Idol" runner-up
• Sam Dees, soul music singer
• Dennis Edwards, soul music singer
• Paul Finebaum, radio talk-show host
• Fannie Flagg, author, actress
• Louise Fletcher, actress
• Emmylou Harris, singer
• Erskine Hawkins, jazz composer
• Taylor Hicks, soul music singer, American Idol winner
• Odetta Holmes, folk singer
• Alan Hunter, former MTV VJ
• Kate Jackson, actress
• Eddie Kendricks, soul music singer
• Rebecca Luker, singer, actress
• Gucci Mane, rapper
• Mark & Brian, radio personalities
• Gail Patrick, actress, television producer
• Wayne Rogers, actor
• Vincent Saizis, cinematographer
• Glenn Shadix, actor (Bessemer)
• Ruben Studdard, singer, American Idol winner
• Sun Ra, musician
• Matt Whitson, musician, producer
• Paul Williams, soul music singer
• Tammy Wynette, country singer

Law & Politics

• Truman H. Aldrich, U.S. Representative
• Richard Arrington, first African-American mayor of Birmingham
• Spencer Bachus, U.S. Representative
• Sydney J. Bowie, U.S. Representative
• B. B. Comer, Governor of Alabama
• Eugene "Bull" Connor, former Commissioner of Public Safety
• Norman Lee Cooper, President of American Bar Association
• Russell McWhortor Cunningham, Governor of Alabama
• William Henry Denson, U.S. Representative
• Art Hanes, mayor of Birmingham
• Earl F. Hilliard, U.S. Representative
• George Huddleston, U.S. Representative
• George Huddleston, Jr., U.S. Representative
• Joseph Forney Johnston, Governor of Alabama, U. S. Senator
• Bernard Kincaid, mayor of Birmingham
• Chris McNair, Jefferson County Commissioner
• John P. Newsome, U.S. Representative
• Luther Patrick, U.S. Representative
• Cecil F. Poole, federal judge, U.S. Court of Appeals for the Ninth Circuit
• Charles Redding Pitt, chairman of Alabama Democratic Party
• Condoleezza Rice, U.S. Secretary of State
• Richard Shelby, U.S. Senator
• Jesse F. Stallings, U.S. Representative
• Margaret Tutwiler, diplomat
• Oscar Underwood, U. S. Senator
• Donald Watkins, attorney, banker
• William Edgar Weldon, politician, real estate developer
• Frank S. White, U. S. Senator

Math & Science

• Lawrence J. DeLucas, biophysical engineer, Columbia astronaut.
• E. O. Wilson, entomologist and noted author

Medicine

• James Andrews, nationally renowned orthopedic specialist
• S. Richardson Hill, endocrinologist and health care
• dministration expert
• John W. Kirklin, pioneering heart surgeon
• Larry Lemak, orthopedist and entrepreneur
• Albert Pacifico, renowned heart surgeon
• Luther Leonidas Terry, former Surgeon General of the United States
• Joseph F. Volker, dental researcher, first president of UAB

Sports

• Mike Anderson, former UAB basketball coach
• Charles Barkley, basketball player
• Gene Bartow, former basketball coach and Athletic Director for UAB
• Bruce Benedict, born in Birmingham, major league baseball player
• Lyman Bostock, born in Birmingham, major league baseball player
• Bobby Bowden, football coach
• Bear Bryant, football coach
• Bubba Church, born in Birmingham, major league baseball player
• Karlos Dansby, football player
• Spud Davis, born in Birmingham, major league baseball player
• Tom Drake, born in Birmingham, major league baseball player
• Vonetta Flowers, Olympic Gold-medalist and bobsledder
• Alex Grammas, born in Birmingham, major league baseball player
• Hubie Green, professional golfer
• Jerry Hairston, born in Birmingham, major league baseball player
• Samuel H. Hairston, baseball player
• Bobby Humphrey, University of Alabama football player, Miami Dolphins, Denver Broncos
• Bo Jackson, multi-sport athlete
• Ron Jackson, born in Birmingham, major league baseball player
• Carl Lewis, track and field athlete
• Theodore Long, current general manager of WWE Smackdown!
• Lee May, born in Birmingham, major league baseball player
• Willie Mays, baseball player
• Tony Nathan, football player and coach
• Gus Niarhos, born in Birmingham, major league baseball player
• Satchel Paige, baseball player
• Erk Russell football player
• Jason Standridge, major league baseball player
• Ronald Steele, Basketball player
• Virgil Tucks, born in Birmingham, major league baseball player
• Bob Veale, born in Birmingham, major league baseball player
• Al Worthington, born in Birmingham, major league baseball player
• Dixie Walker, baseball player
• Mike Davis, UAB basketball coach

Other

• Mother Angelica, nun and founder of global Catholic network EWTN
• Angela Davis, activist
• Deidre Downs, Miss America 2005
• Patti Ruffner Jacobs, social reformer
• Wallace Rayfield. architect
• Joseph Raya, archbishop and social activist
• Fred Shuttlesworth, Civil Rights activist
• Heather Whitestone, Miss America 1995
• Louise Wooster, famed madam
• Haleigh Stidham, Miss Alabama USA 2006
• Jay Sebring, ex-boyfriend of Sharon Tate and Charles Manson victim.